• Users Online: 540
  • Print this page
  • Email this page
ORIGINAL ARTICLE
Year : 2013  |  Volume : 4  |  Issue : 1  |  Page : 3

Ischemia modified albumin and nitric oxide in diabetic nephropathy


1 Department of Biochemistry, Pt. B.D.Sharma PGIMS, Rohtak, Haryana - India
2 Department of Biochemistry, Lady Hardinge Medical College, New Delhi - India
3 Department of Medicine, Pt. B.D. Sharma PGIMS, Rohtak, Haryana - India
4 Department of Radiotherapy, Pt. B.D. Sharma PGIMS, Rohtak, Haryana - India

Correspondence Address:
K Dahiya
Associate Professor Department of Biochemistry, Pt. B.D.Sharma PGIMS, Rohtak, Haryana - India

Login to access the Email id

Source of Support: None, Conflict of Interest: None


Rights and PermissionsRights and Permissions

Diabetes is associated with complications related to ischemia and oxidative stress. Diabetic nephropathy is one of the common vascular complications. The aim of the study was to evaluate the levels of ischemia modified albumin and nitric oxide in patients with diabetic nephropathy. Serum levels of ischemia modified albumin and nitric oxide were estimated in fifty patients with diabetic nephropathy and fifty patients with uncomplicated diabetes along with routine biochemistry investigations and compared with thirty healthy controls. The correlation of micoalbuminuria with ischemia modified albumin and nitric oxide was also calculated in patients with diabetic nephropathy. The levels of ischemia modified albumin and nitric oxide were found to be raised (p < 0.001) in patients with diabetic nephropathy as compared to uncomplicated diabetes and healthy controls. A positive correlation of these parameters was observed with microabuminuria. Thus, estimation of ischemia modified albumin and nitric oxide may help in better understanding of etiopathogenesis of diabetic nephropathy and may act as markers for this condition, if supported by further research.


[PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed1135    
    Printed88    
    Emailed2    
    PDF Downloaded150    
    Comments [Add]    

Recommend this journal