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ORIGINAL ARTICLE
Year : 2014  |  Volume : 5  |  Issue : 3  |  Page : 3

Factors screening the peripheral neuropathy in asymptomatic patients with type 2 diabetes by Neurothesiometer


1 Department of Medicine, Baqai Institute of Diabetology and Endocrinology, Baqai Medical University, Karachi - Pakistan
2 Department of Medicine, Baqai Medical University, Karachi - Pakistan
3 Research Department, Baqai Institute of Diabetology and Endocrinology, Baqai Medical University, Karachi - Pakistan
4 Research Department, Baqai Institute of Diabetology and Endocrinology, Baqai Medical University, Karachi; Department of Bio-Chemistry, Baqai Medical University, Karachi - Pakistan

Correspondence Address:
A B Zafar
Department of Medicine, Baqai Institute of Diabetology and Endocrinology, Baqai Medical University, Karachi - Pakistan

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Source of Support: None, Conflict of Interest: None


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To identify the feet at risk of developing foot ulceration in asymptomatic Type 2 diabetic patients using vibration perception thresholds. This study was conducted at Baqai Institute of Diabetology & Endocrinology (BIDE) over a period of 12 months from October 2009 to September 2010. A total of 99 patients were selected from the outpatient department after obtaining informed consent. Detailed history, physical examination including foot examination was carried out. All asymptomatic patients with Type 2 diabetes were considered eligible to participate in the study of Vibration Perception Threshold (VPT) obtained by Neurothesiometer. A cut off value of 25 V was used to identify feet at risk. Patients with Type 1 or Type 2 diabetes having present or previous history of foot ulcer, patients above 70 years of age, having painful neuropathy, chronic renal disease, chronic liver disease or congestive heart failure were excluded from the study. Out of 99 patients, 49 were males and 50 were females. More than half were above the age of 40 years, 33 subjects were between 40-50 years of age followed by 30 subjects in the age group of 51-60 years. Mean duration of diabetes was 7.65 ± 5.51 years. 10% of subjects showed VPT > 25. Among different variables, only duration of diabetes showed significant correlation with increased VPT. This study concludes that a significant number of asymptomatic Type 2 diabetic patients may have early stage of sensory neuropathy. VPT is an effective tool for identifying feet at risk of foot ulceration in asymptomatic patients.


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