Journal of Diabetology

ORIGINAL ARTICLE
Year
: 2017  |  Volume : 8  |  Issue : 1  |  Page : 18--21

Glycated haemoglobin: A marker of circulating lipids in patients with type 2 diabetes


Sheikh Ishaq1, Iram Shabir1, Arif A Bhat1, Imran Shafi1, Saima Mushtaq1, Parvaiz A Shah2, Azra Baba3, Sabhiya Majid1 
1 Department of Biochemistry, Government Medical College, Srinagar, Jammu and Kashmir, India
2 Department of Medicine, Government Medical College, Srinagar, Jammu and Kashmir, India
3 Department of Biochemistry, Sai Institute of Paramedical and Allied Sciences, Dehradun, Uttarakhand, India

Correspondence Address:
Sabhiya Majid
Department of Biochemistry, Government Medical College, Srinagar, Jammu and Kashmir
India

Introduction: Type 2 diabetes mellitus (T2DM) is a group of metabolic disorder and is an independent risk factor for cardiovascular disease and dyslipidaemia. Patients with T2DM have dyslipidaemia at wavering degrees, characterised by increased levels of triglyceride and low-density lipoprotein-cholesterol and decreased levels of high-density lipoprotein (HDL)-cholesterol. In the present study, we evaluated glycated haemoglobin (HbA1c) as a marker of circulating lipids in patients with T2DM. Methods: Two hundred and thirty-nine patients with T2DM were enrolled for the study. A detailed biochemical and lipid profile was done for all patients. Results: Of 239 cases, 96 (40%) were male and 143 (60%) were female. Of 239 patients, 53 (22%) patients with T2DM had controlled glycaemia (HbA1c <6.5) and 186 (78%) patients had uncontrolled glycaemia (HbA1c ≥6.5). Pearson's correlation of HbA1c with all lipid parameters was statistically significant. HbA1c, however, had an inverse correlation with HDL and had a significant direct correlation with fasting blood glucose. Conclusion: The study reveals that HbA1c is not only a reliable glycaemic index but can also be used as an important indicator of dyslipidaemia in patients with T2DM.


How to cite this article:
Ishaq S, Shabir I, Bhat AA, Shafi I, Mushtaq S, Shah PA, Baba A, Majid S. Glycated haemoglobin: A marker of circulating lipids in patients with type 2 diabetes.J Diabetol 2017;8:18-21


How to cite this URL:
Ishaq S, Shabir I, Bhat AA, Shafi I, Mushtaq S, Shah PA, Baba A, Majid S. Glycated haemoglobin: A marker of circulating lipids in patients with type 2 diabetes. J Diabetol [serial online] 2017 [cited 2020 Jun 6 ];8:18-21
Available from: http://www.journalofdiabetology.org/article.asp?issn=2078-7685;year=2017;volume=8;issue=1;spage=18;epage=21;aulast=Ishaq;type=0