Journal of Diabetology

REVIEW ARTICLES
Year
: 2021  |  Volume : 12  |  Issue : 2  |  Page : 114--119

Inhaled glucagon: A new hope for severe hypoglycemia in type 1 diabetes


Salva Fatima Heba, Uzma Parveen, Sara Sana Ayesha Khanum, Maaria Gulnaaz, Maimuna Tabassum, Syeda Batool Safiyya 
 Department of Pharmacy Practice, Deccan School of Pharmacy, Hyderabad, Telangana, India

Correspondence Address:
Salva Fatima Heba
Department of Pharmacy Practice, Deccan School of Pharmacy, Darussalam, Aghapura, Hyderabad 500002, Telangana.
India

Until now injectable glucagon was the only available treatment used in the management of severe hypoglycemia wherein glucagon had to be prepared in several steps before administration. This method of delivery of injectable glucagon being cumbersome and unappealing for a wide majority of the patients had led to a search for an alternative route of drug delivery. Intranasal (IN) glucagon now serves an efficient, safe, easy to administer, and a favorable substitute to glucagon injections. This ready-to-use device stands in clear contrast to overcome the limitations associated with the currently available glucagon preparations, which has emerged a key advancement in the management of severe hypoglycemia in adolescents and children with type 1 diabetes. IN glucagon is now being developed and studied in other countries as well to meet the unmet need for an easy and convenient glucagon administration. This review covers the basic information of nasal glucagon, trials on nasal glucagon in children’s and adults, and its potential uses, limitations, and future scope in practice.


How to cite this article:
Heba SF, Parveen U, Khanum SS, Gulnaaz M, Tabassum M, Safiyya SB. Inhaled glucagon: A new hope for severe hypoglycemia in type 1 diabetes.J Diabetol 2021;12:114-119


How to cite this URL:
Heba SF, Parveen U, Khanum SS, Gulnaaz M, Tabassum M, Safiyya SB. Inhaled glucagon: A new hope for severe hypoglycemia in type 1 diabetes. J Diabetol [serial online] 2021 [cited 2021 May 7 ];12:114-119
Available from: https://www.journalofdiabetology.org/article.asp?issn=2078-7685;year=2021;volume=12;issue=2;spage=114;epage=119;aulast=Heba;type=0